Difficult to Express Proteins 2011

More information on Difficult to Express Proteins

KEYNOTE Presentation

Novel Tools for the Overexpression of Transport Proteins

Raimund Dutzler, Ph.D., Professor, Biochemistry, University of Zurich
The recent success in the structure determination of membrane proteins is tied to the possibility to characterize large numbers of homologues of a particular protein family in different expression systems to identify candidates with superior biochemical properties. I will discuss a novel tool that allows the rapid generation of expression constructs for all common pro- and eukaryotic expression systems and discuss its application to different ion transport families.