Biomarker Assay Development 2011
January 31 - February 2, 2011
San Diego CA , USA
FEATURED PRESENTATION
Safety Biomarkers in Action: Pre-Clinical to Clinical Translation
Calvert Louden, M.D., Senior Director of Pathology, Johnson & Johnson Pharmaceuticals
In toxicology (safety) the paradigm of mechanisms, models and markers is relevant to both safety and efficacy. However, the challenges for safety are significant and there is a strong emphasis to develop and employ new Safety Biomarkers (SBM). These new SBMs could contribute significantly to these challenges and be more informative if they can (1) distinguish between adaptive and toxic response (injury); (2) be predictive as well as diagnostic for injury that is minimal, progressive or reversible; (3) influence the selection of monitorable safety biomarkers for Phase 1 and beyond; (4) provide insights into the possible mode of action/mechanism of toxicity.
Safety Biomarkers in Action: Pre-Clinical to Clinical Translation
Calvert Louden, M.D., Senior Director of Pathology, Johnson & Johnson Pharmaceuticals
In toxicology (safety) the paradigm of mechanisms, models and markers is relevant to both safety and efficacy. However, the challenges for safety are significant and there is a strong emphasis to develop and employ new Safety Biomarkers (SBM). These new SBMs could contribute significantly to these challenges and be more informative if they can (1) distinguish between adaptive and toxic response (injury); (2) be predictive as well as diagnostic for injury that is minimal, progressive or reversible; (3) influence the selection of monitorable safety biomarkers for Phase 1 and beyond; (4) provide insights into the possible mode of action/mechanism of toxicity.
Venue
Location: Hilton San Diego Resort & Spa
The Hilton San Diego Resort & Spa offers the perfect meeting destination to balance business with pleasure. The resort features more than 18,000 square feet of indoor function space, in addition to..
Contact
1775 E Mission Bay Dr., Mission Bay San Diego , USA
1-619-276-4010
1-619-276-4010
Related events
Biomarker Assay Development January 31 - 2, 2012
Biomarker Assay Development January 31 - February 2, 2011
