Protein-Protein Interactions as Drug Targets 2011
April 13 - 14, 2011
San Dirgo CA , Etats-Unis d’Amérique
Identifying Extracellular Protein Interactions Using a Secreted Protein Microarray Platform
Technologies for identifying protein-protein interactions are largely biased towards intracellular binding partners. To address extracellular protein interactions, we have developed a secreted-protein microarray and validated its use as a fast and robust method for identifying receptor-ligand interactions. A set of eighty-nine immunoglobulin-domain receptors was screened and used to establish a scoring and specificity algorithm that revealed top hits as known binding partners and several new interactions for functional validation.
Technologies for identifying protein-protein interactions are largely biased towards intracellular binding partners. To address extracellular protein interactions, we have developed a secreted-protein microarray and validated its use as a fast and robust method for identifying receptor-ligand interactions. A set of eighty-nine immunoglobulin-domain receptors was screened and used to establish a scoring and specificity algorithm that revealed top hits as known binding partners and several new interactions for functional validation.
Lieux de Rendez-Vous
Location: Hilton San Diego Resort & Spa
The Hilton San Diego Resort & Spa offers the perfect meeting destination to balance business with pleasure. The resort features more than 18,000 square feet of indoor function space, in addition to..
Contact
1775 E Mission Bay Dr., Mission Bay San Diego , USA
1-619-276-4010
Evénements Liés
Protein-Protein Interactions as Drug Targets April 17 - 18, 2013
Protein-Protein Interactions as Drug Targets 17 April, 2012
Protein-Protein Interactions as Drug Targets April 13 - 14, 2011