Conference · Boston, Massachusetts

Difficult to Express Proteins

Health · Medicine · Laboratory

Official website
Next editionNot confirmedLast edition we have: 29–30 Apr 2015
Last venueSeaport World Trade Center BostonBoston, Massachusetts · where the 2014 edition was; venue not yet confirmed
RunningSince 2011Annual · 5 editions on record
Last checked12 Nov 2026Organiser website checked
We haven't confirmed the next dates yet. The last edition in our records was 29–30 Apr 2015 at Seaport World Trade Center Boston. Check the organiser's site: pegsummit.com. Are you the organiser? Correct this listing.

Key numbers

Editions on record
5first in 2011

About Difficult to Express Proteins

Cambridge Healthtech Institute’s Ninth Annual

Difficult to Express Proteins

Harnessing Innovation to Improve Expression and Function

Part of the Tenth Annual PEGS: the essential protein engineering summit

May 5-6, 2014 | Seaport World Trade Center | Boston, MA

Membrane proteins, ion channels, toxic or insoluble proteins, low abundance protein complexes, vaccines and other “finicky” proteins often are the best choices for therapeutics, yet their successful expression is a minefield of failures and challenges. This conference will present innovative and imaginative methods to make those difficult to express proteins more “expressible” and functional.

Topics will include, but are not limited to:

Novel host, vector, transfection and cloning strategies

Solving problems in recombinant protein expression

Cell-free methods for finicky proteins

Controlling disulfide bonds

Folding, refolding and function

Improving expression of extra-cellular proteins

Rational vector design and pathway modulation to facilitate expression of difficult proteins

Utilizing transient gene expression

Achieving proper glycosylation, pegylation, sialylation, etc.

Expression of protein complexes and toxic proteins

Overcoming ion channel expression problems

From our listing of the 2014 edition. Details may have changed since.

Editions

YearDatesWhereExhibitorsVisitors
201529–30 Apr 2015Seaport World Trade Center Boston
Boston, Massachusetts
——
20145–6 May 2014Seaport World Trade Center Boston
Boston, Massachusetts
——
201329–30 Apr 2013Seaport World Trade Center Boston
Boston, Massachusetts
——
201230 Apr – 1 May 2012Boston Park Plaza Hotel
Boston, Massachusetts
——
20119–10 May 2011Sheraton Boston Hotel & Towers
Boston, Massachusetts
——

Past editions from the bvents archive (2008–2019) and organiser figures where they were published.

Questions

When is Difficult to Express Proteins?

The next dates haven't been confirmed. The last edition we have on record was 29–30 Apr 2015.

Where is it held?

The 2014 edition was at Seaport World Trade Center Boston, Boston, Massachusetts. The organiser hasn't confirmed the venue for this edition yet.

How often does it take place?

Annual, judging by the 5 editions on record since 2011.

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